Advanced Genetics

A survey of experimental approaches in genetics, from classical screens to genome-wide analyses, examining a variety of genetic model organisms and their specific applications, cytogenetics, chromosomal abnormalities and associated genetic counselling issues in humans. Fundamentals are applied to searches for complex disease genes, and understanding genetic variation in human populations.

Course overview

Points

20

Fees

$1128.4 NZD

International fees

$4836.4 NZD

Course offered in

  • Trimester 1

Duration

1 trimester

Prerequisites

BIOL/BMSC 241;

Co-requisites

Restrictions

BIOL 343, BIOL/BMSC 341, 342

Taught by

The School of Biological Sciences

Science

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Course content

Weeks 1-5: Andrew Munkacsi Genetics of ageing, model organisms, molecular causes of ageing, mitochondrial dysfunction, DNA repair, telomeres, caloric restriction, insulin-like pathways, sirtuin, autophagy, centenarian genetics, premature ageing, cholesterol homeostasis, lipotoxicity.
Weeks 6-9: Melanie McConnell Cancer genomes, epigenetics, chromatin structure and cancer. Cancer genes and inherited predisposition, genetics of sporadic cancers, targeting cancer genes.
Weeks 10-12: Andrew Munkacsi Genetics, animal models, cell biology, and genetic risk factors of Alzheimer’s disease. Personalised medicine, human microbiome.

Course learning objectives

Students who pass this course will be able to:

  1. explain classical and contemporary methods of genetic analysis and their application in genetic model systems

  2. apply the information relevant to human genetics, both at the population and individual levels, with the ultimate goal of gaining an improved understanding of the genetic basis of human health and disease

Available offerings

Please select an offering from the list below to view more details about this course.

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Offering CRN 19861

This course outline is final and archived.

Duration

6 March 2017 - 5 July 2017

Starts

Trimester 1

Campus

Kelburn

Lecture start times

Monday - 15:10, 15:10

Tuesday - 14:10, 14:10

Friday - 14:10, 14:10

People

Lecturers

Andrew Munkacsi's portrait'

Andrew Munkacsi

David Maass's portrait'

David Maass

Schedule

Lectures be made available on blackboard in the “Lectures” section.

  • Week 1

    Lecture

    Lecture

    Andrew Munkacsi

    6 March

    Lecture

    Lecture

    Andrew Munkacsi

    7 March

    Lecture

    Lecture

    Andrew Munkacsi

    10 March

  • Week 2

    Lecture

    Lecture

    Andrew Munkacsi

    13 March

    Lecture

    Lecture

    Andrew Munkacsi

    14 March

    Lecture

    Lecture

    Andrew Munkacsi

    17 March

  • Week 3

    Lecture

    Lecture

    Andrew Munkacsi

    20 March

    Lecture

    Lecture

    Andrew Munkacsi

    21 March

    Lecture

    Lecture

    Andrew Munkacsi

    24 March

  • Week 4

    Lecture

    Lecture

    Andrew Munkacsi

    27 March

    Lecture

    Lecture

    Andrew Munkacsi

    28 March

    Lecture

    Lecture

    Andrew Munkacsi

    31 March

  • Week 5

    Lecture

    Lecture

    Melanie McConnell

    3 April

    Test

    Test 1

    4 April

    Laboratory

    Lab Stream A - KK701

    5 April

    Laboratory

    Lab Stream B - KK701

    6 April

    Lecture

    Lecture

    Melanie McConnell

    7 April

  • Week 6

    Lecture

    Lecture

    Melanie McConnell

    10 April

    Lecture

    Lecture

    Melanie McConnell

    11 April

    Laboratory

    Lab Stream A - KK701

    12 April

    Laboratory

    Lab Stream B - KK701

    13 April

    Break

    No class

    Melanie McConnell

    14 April

  • Week 7

    Lecture

    Lecture

    Melanie McConnell

    1 May

    Lecture

    Lecture

    Melanie McConnell

    2 May

    Laboratory

    Lab Stream A - KK217/218

    3 May

    Laboratory

    Lab Stream B - KK217/218

    4 May

    Lecture

    Lecture

    Melanie McConnell

    5 May

  • Week 8

    Lecture

    Lecture

    Melanie McConnell

    8 May

    Lecture

    Lecture

    Melanie McConnell

    9 May

    Laboratory

    Lab Stream A - KK217/218

    10 May

    Lecture

    Lab Stream B - KK217/218

    11 May

    Lecture

    Lecture

    Melanie McConnell

    12 May

  • Week 9

    Test

    Test 2/Lecture

    Melanie McConnell

    15 May

    Lecture

    Lecture

    Andrew Munkacsi

    16 May

    Lecture

    Lecture

    Andrew Munkacsi

    19 May

  • Week 10

    Lecture

    Lecture

    Andrew Munkacsi

    22 May

    Lecture

    Lecture

    Andrew Munkacsi

    23 May

    Lecture

    Lecture

    Andrew Munkacsi

    26 May

  • Week 11

    Lecture

    Lecture

    Andrew Munkacsi

    29 May

    Lecture

    Lecture

    Andrew Munkacsi

    30 May

    Lecture

    Lecture

    Andrew Munkacsi

    2 June

  • Week 12

    Break

    No class

    5 June

    Lecture

    Lecture

    Andrew Munkacsi

    6 June

    Lecture

    Lecture

    Andrew Munkacsi

    9 June

6 March 2017
Course begins

6 March 2017 to 9 June 2017
Teaching
14 April 2017 to 28 April 2017
Break
12 June 2017 to 15 June 2017
Study period
16 June 2017 to 5 July 2017
Exam period
5 July 2017
Course ends

  • 6 March 2017 - 16 April 2017

    • Monday
      • 15:10 - 17:00 – LT119, Hunter, Kelburn
    • Tuesday
      • 14:10 - 15:00 – LT220, Hunter, Kelburn
    • Friday
      • 14:10 - 15:00 – LT119, Hunter, Kelburn
  • 1 May 2017 - 11 June 2017

    • Monday
      • 15:10 - 17:00 – LT119, Hunter, Kelburn
    • Tuesday
      • 14:10 - 15:00 – LT220, Hunter, Kelburn
    • Friday
      • 14:10 - 15:00 – LT119, Hunter, Kelburn

Teaching format

The course will be taught by way of three 1-hour lectures per week and four 3-hour laboratory sessions.

Workload

The course has a value of 20 points and with a single point equivalent to 10 hours work the course workload including lectures, laboratories and personal study time is around 200 hours.

Additional classes

Laboratories: Stream A on Wednesday and Stream B on Thursday; each stream meets at 10:00-12:50 and 14:10-17:00 (Weeks 5 and 6 in KK701) as well as at 11:00-13:50 and 15:10-18:00 (Weeks 7 and 8 in KK217/218)

Texts

Required

There are no required texts for this offering.

Recommended

Any of the following are recoomended to supplement lectures:

  • “iGenetics: A Molecular Approach”  by Peter J. Russell, 3rd ed., 2010
  • "Human Genetics: Concepts and Applications" by Ricki Lewis, 10th ed., 2011
  • "Human Genetics and Genomics" by Bruce R. Korf, 4th ed., 2013
  • "Human Molecular Genetics" by Tom Strachan and Andrew P. Read, 4th ed., 2010

Required materials and equipment

Assessment

Assessment will be as follows:

  • Test 1

    CLO:

    • 1,
    • 2,

    Mark: 10%

  • Test 2

    CLO:

    • 1,
    • 2,

    Mark: 10%

  • Final Exam (Comprehensive)

    CLO:

    • 1,
    • 2,

    Mark: 40%

  • Quizzes

    CLO:

    • 1,
    • 2,

    Mark: 10%

  • Debate

    CLO:

    • 1,
    • 2,

    Mark: 5%

  • Lab report 1

    CLO:

    • 1,
    • 2,

    Mark: 12.5%

  • Lab report 2

    CLO:

    • 1,
    • 2,

    Mark: 12.5%

Mandatory requirements

In addition to achieving an overall pass mark of at least 50%, students must:

  • Achieve at least 50% in the final examination
  • attend all four laboratory sessions

If you believe that exceptional circumstances may prevent you from meeting the mandatory course requirements, contact the Course Coordinator for advice as soon as possible.

Marking criteria

Marking criteria will be posted on Blackboard.

Work submission

-

Extension

Requests to sit a ‘makeup’ terms test, or an extension of the due date for an assignment, can be granted only if you have been prevented from attending a test (or completing an item of assessment) because of an illness or injury; personal bereavement; or some other critical personal or exceptional circumstance. The illness or impairment must be verified at the time by supporting documents from a registered health professional (medical practitioner, midwife, dental surgeon, psychologist, or counsellor approved by the Convener of the Academic Committee). In other exceptional circumstances some form of official documentation will be required. Applications must be made within a reasonable time of the assessment date, or in circumstances beyond your control on the day of the assessment.

Penalties

Penalties of 5% per day may be enforced for unjustified late assignments.

Communication and additional information

Course information, other than that given in class, will be made available on Blackboard. Please ensure that you keep a regular watch on the Blackboard site.

Student feedback

Students in 2016 strongly agreed that the way this course was organised helped them prepare for the assessments and learn overall. They were encouraged to think critically, stimulated to learn more, and developed their communication skills. The amount of work was about right for the students. The course will therefore be offered in a similar way for 2016.

You can view Student course feedback collected for the University courses from the last completed trimester for which feedback was collected

Class representative

The class representative provides a useful way to communicate feedback to the teaching staff during the course. They also work with the VUWSA Education Office on any academic issues that arise in their course. Reps are elected by students by the third week of classes every trimester. Being a rep requires a weekly commitment.

The Use of Te Reo Māori for Assessment Policy

Te Herenga Waka—Victoria University of Wellington values te reo Māori. Students who wish to submit any of their assessments in te reo Māori must refer to The Use of Te Reo Māori for Assessment Policy - PDF 134kb

He mea nui te reo Māori ki Te Herenga Waka. Ki te pīrangi koe ki te tuhituhi i ō aro matawai i roto i te reo Māori, tēnā me mātua whakapā atu ki te kaupapa here, The Use of Te Reo Māori for Assessment Policy - PDF 134kb

Course additions and withdrawals

If you want to add or drop a course you need to make sure you follow the correct process.

Important information

Keep your uni experience running smoothly—find out how to manage your studies from enrolment through to graduation.

Find out more:

  • Enrolment and course advice
  • Student conduct and feedback
  • Examinations and assessments