James Mbinta
PhD in Health: Herpes Zoster: Epidemiology and Vaccine Effectiveness and Safety
Profile
James is a full-time doctoral candidate within the School of Health. His doctoral research examines the effectiveness and safety of the zoster vaccines. Herpes zoster (HZ) is characterised by a painful vesicular rash and in older people often leads to post-herpetic neuralgia (PHN), and prolonged pain with a subsequent negative impact on quality of life and functional status. Vaccine efficacy and effectiveness against incident HZ has been demonstrated in clinical trials and observational studies. His objective is to describe the epidemiology of zoster and assess vaccine safety and effectiveness against incident HZ and PHN in adults 50 years and older.
A systematic review will be carried out to evaluate the international evidence on the effectiveness of zoster vaccines. National retrospective observational (2006 – 2018), cohort (2018 – 2020), and self-controlled case series (2018 – 2020) and supervised machine learning studies will be carried out using routinely available data from the Ministry of Health, New Zealand.
Information generated safety, effectiveness, and benefits of the zoster vaccine will be vital for informing policy makers, health practitioners and the public of the relative benefits of the vaccination programme and have potentially large societal benefits for NZ and the international scientific community.
Qualifications
Master of Public Health, Institute of Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam
Doctor of Medicine, Faculty of Health Sciences, University of Buea, Buea, Cameroon
Research interests
Epidemiology
Publications
Pine, R., Mbinta, J., Te Morenga, L., & Fleming, T. (2021). A Casual Video Game with Psychological Well-being Concepts for Young Adolescents: Protocol for an Acceptability and Feasibility Study. JMIR Res Protoc, 10(8), e31588. doi:10.2196/31588.
Mbinta, J. F., Nguyen, B. P., Awuni, P. M. A., Eme, P. E., & Simpson, C. R. (2021). Postlicensure herpes zoster vaccine effectiveness: systematic review protocol. BMJ Open, 11(2), e040964. doi:10.1136/bmjopen-2020-040964.
Nguyen, Q. H., Nguyen, B. P., Nguyen, T. B., Do, T. T. T., Mbinta, J. F., & Simpson, C. R. (2021). Stacking segment-based CNN with SVM for recognition of atrial fibrillation from single-lead ECG recordings. Biomedical Signal Processing and Control, 68, 102672. doi: 10.1016/j.bspc.2021.102672
Pine, R., Mbinta, J., Te Morenga, L., & Fleming, T. (2021). A Casual Video Game With Psychological Well-being Concepts for Young Adolescents: Protocol for an Acceptability and Feasibility Study (Preprint). doi:10.2196/preprints.31588
Amaltinga APM, Mbinta JF. (2020). Factors associated with depression among young people globally: a narrative review. Int J Community Med Public Health 2020; 7:3711-21
Awuni PMA., Mbinta FJ., Abugri OB. (2020). Factors influencing contraceptive use among women of reproductive age in the Bia West District of Ghana: A community-based cross-sectional study. World Journal of Advance Healthcare Research, 4(2), 121130.
Mbinta Fenibe James, Pham Quang Thai, Dao Thi Minh An, Marc Choisy, Phan Hong Hai, and Tran Nhu Duong (2018). Modelling of Hand Foot and Mouth Disease in Hai Phong, Vietnam, 2012 – 2016. JMR 116 E3 (7), 75 – 86.
Mbinta JF, Nguyen BP, Awuni PMA, Paynter J, Simpson CR. Post-licensure zoster vaccine effectiveness against herpes zoster and postherpetic neuralgia in older adults: a systematic review and meta-analysis. The Lancet Healthy Longevity. 2022;3(4):e263-e75.
Mbinta, J. F., Wang, A. X., Nguyen, B. P., Paynter, J., Awuni, P. M. A., Pine, R., Sporle, A. A., & Simpson, C. R. (2022). Herpes zoster vaccine effectiveness against herpes zoster and postherpetic neuralgia in New Zealand: A retrospective cohort study. The Lancet Regional Health – Western Pacific.
Pine, R., Bruckner, K., Mbinta, J., Twemlow, R., & Anderson, S. (2022). Perceptions of Parents and Caregivers in New Zealand: Educational Experiences of their Children with Tourette Syndrome. International Journal of Disability, Development and Education, 1-14.
Mbinta, J., Wang, A., Nguyen, B., Paynter, J., Awuni, P. M., Pine, R., Sporle, A., & Simpson, C. (2022). Zoster vaccine effectiveness against Zoster and Postherpetic Neuralgia in New Zealand: a retrospective cohort study Australasian Association for Academic Primary Care (AAAPC) Annual Research Conference, 18-19 August 2022, Australian Journal of Primary Health.
Contact
mbinta.james@vuw.ac.nz
Supervisors
Associate Dean, Research
Wellington Faculty of Health
