mRNA malaria vaccine
Learn more about how the mRNA and lipid nanoparticles team is developing an mRNA vaccine to overcome the limitations of traditional malaria vaccines.

The problem
Despite decades of research, traditional malaria vaccines have limitations, including poor efficacy and interference from previous infection.
The solution
We developed an mRNA vaccine incorporating a potent vaccine adjuvant which enables the generation of liver-resident memory T cells to prevent malaria.
The impact
Our mRNA vaccine shows promise for effective protection against malaria, particularly in malaria-endemic regions, as it is not impaired by previous exposure to blood-stage infection, unlike traditional vaccines.
Research team
mRNA and lipid nanoparticles team
Design and synthesis of vaccine adjuvants and ionisable lipids used in vaccines.
Read moreLatest publications 2023
Nat Immunol (2023)